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4951 Arbaclofen placarbil
3e1d7d82de248ad6b105f02cc6b39c79b3d496d152797bb696d10a14ef660e5c

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Properties

Chemistry

Arbaclofen placarbil ( , also known as XP19986) is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials.

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